I got my iPhone 4S today. Same issue with my 2011 SRX bluetooth. When I manually picked-up the phone and went to the home screen, then pressed the steering wheel phone call button (voice, bluetooth) it would work. If it was in a sub-menu, it did not work. I could not make two calls in a row without picking up the 4s and pressing the home screen button. My Blackberry was bullet proof and this was seem very shaky. Using the same process, I was also able to ask Siri the time in Beijing China (as a test). It answered correctly and hung immediately up. I called GM and they said their logs are FILLED with 4s problems and upset customers.